Microsatellite instability in ductal carcinoma in situ of the breast.

doi:10.1002/(SICI)1096-9896(199805)185:1<18::AID-PATH41>3.0.CO;2-G

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Article

Microsatellite instability in ductal carcinoma in situ of the breast.

The Journal of pathology - 1 May 1998

Walsh T, Chappell S A, Shaw J A, Walker R A

Abstract excerpt

Microsatellite instability (MI+) is associated with defects in mismatch repair, resulting in a 'mutator' phenotype and the development and progression of cancer. MI+ has been documented in invasive breast carcinomas. This study was undertaken to determine whether MI+ is found in the early non-inv...

Topics

Breast Neoplasms
Carcinoma in Situ
Carcinoma, Ductal, Breast
DNA Repair
Humans
Immunoenzyme Techniques
Loss of Heterozygosity
Microsatellite Repeats
Mutation
Neoplasm Proteins
Receptor, ErbB-2
Tumor Suppressor Protein p53

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