Article
Soluble fumarate reductase isoenzymes from Saccharomyces cerevisiae are required for anaerobic growth.
FEMS microbiology letters - 1 Aug 1998
Arikawa Y, Enomoto K, Muratsubaki H, Okazaki M
Abstract excerpt
In Saccharomyces cerevisiae, the cytosolic and promitochondrial isoenzymes of fumarate reductase are encoded by the FRDS and OSM1 genes, respectively. The product of the OSM1 gene is reported to be required for growth in hypertonic medium. Simultaneous disruption of the FRDS and OSM1 genes resulted in the inability of the yeasts to grow anaerobically on glucose as a carbon source, and disruption of the OSM1 gene...
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