Article
ACE/DD genotype is associated with hemostasis balance disturbances reflecting hypercoagulability and endothelial dysfunction in patients with untreated hypertension.
American heart journal - 1 Nov 2000
Makris T K, Stavroulakis G A, Dafni U G, Gialeraki A E, Krespi P G, Hatzizacharias A N, Tsoukala C G, Vythoulkas J S, Kyriakidis M K
Abstract excerpt
BACKGROUND: Angiotensin-converting enzyme (ACE) gene polymorphism has been associated with an increased incidence of myocardial infarction. Recent studies have investigated a potential influence of ACE gene polymorphism on fibrinolysis or endothelial function. It has been previously established that essential hypertension is accompanied by endothelial dysfunction and fibrinolytic balance disorders. The aim of our...
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