Gene-environment interaction in Alzheimer's disease: a potential role for cholesterol.

doi:10.1159/000026175

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Article

Gene-environment interaction in Alzheimer's disease: a potential role for cholesterol.

Neuroepidemiology - 1 Jan 1998

Chandra V, Pandav R

Abstract excerpt

Alzheimer's disease is probably a complex disease caused by an interaction of multiple environmental and genetic factors. Genetic defects include 'causative' genes which are rare and a 'susceptibility' gene (sigma4 allele of apolipoprotein E) which is more common in cases. Recent research suggest...

Topics

Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Apolipoproteins E
Cholesterol, HDL
Environment
Female
Humans
Male
Point Mutation

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