[Familial cortisol resistance and mutations of the glucocorticoid receptor gene].

Article

[Familial cortisol resistance and mutations of the glucocorticoid receptor gene].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1998

Iida S, Fujii H, Moriwaki K

Abstract excerpt

Patients with familial cortisol resistance have continuously elevated serum cortisol without any clinical manifestations of Cushing's syndrome due to hyposensitivity to cortisol in all tissues including the hypothalamus and the pituitary. Clinical symptoms of the disease are hypertension with hyp...

Topics

Fatigue
Female
Humans
Hydrocortisone
Hypertension
Hypokalemia
Mutation
Receptors, Glucocorticoid
Renin
Virilism

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