Article
[Adrenocorticotropin receptor in familial glucocorticoid deficiency].
Nihon rinsho. Japanese journal of clinical medicine - 1 Oct 1993
Takayanagi R, Sakai Y, Nawata H, Nishiyama S, Ito T, Kodama M, Matsuda I, Matsuda H
Abstract excerpt
Recent studies have revealed the presence of four subtypes for the melanocortin receptor (MC-R). Among these MC-Rs, MC2-R is considered to be an adrenocorticotropin (ACTH) receptor because its expression is almost localized in the adrenal cortex. Five Japanese patients with ACTH unresponsiveness were examined as to whether they have mutations in the putative ACTH receptor. Among these patients, there are two...
Topics
- Adrenal Cortex
- Amino Acid Sequence
- Glucocorticoids
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Receptors, Corticotropin
- Signal Transduction