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Article

Glucocorticoid resistance syndrome: A diagnostic and therapeutic approach.

Best practice & research. Clinical endocrinology & metabolism - 1 Dec 2006

van Rossum Elisabeth F C, Lamberts Steven W J

Abstract excerpt

In the past decades, several cases of the syndrome of generalized glucocorticoid (GC) resistance have been reported. This familial disease is characterized by reduced cortisol effects, due to a GC receptor (GR) defect, which is compensated by hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis. As a consequence, patients present with signs of adrenal overproduction of mineralocorticoids (hypertension...

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Identifiers

PMID: 17161335
DOI: 10.1016/j.beem.2006.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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