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Article

[Endothelin B receptor system and Hirschsprung disease].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1998

Inoue M, Kusafuka T, Okada A

Abstract excerpt

Hirschsprung disease is a congenital malformation caused by the absence of ganglion cells in the myenteric and submucosal neural plexuses of gut. Mutations in the endothelin-Beta receptor (EDNRB) and endothelin-3(EDN3) genes as well as in the RET, glial-cell-derived neurotrophic factor and sox 10 genes have been shown to be responsible for this disease. These genes are involved in the development of intestinal...

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Source

Identifiers

PMID: 9702069

Genes

EDN3
EDNRB
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Endothelin B receptor system and Hirschsprung disease].PMID 9702069Read ↗

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[The role of ret gene in the pathogenesis of Hirschsprung disease].Semantic proximity Read ↗

Altered endothelin-3 and endothelin-B receptor mRNA expression in Hirschsprung's disease.Semantic proximity Read ↗

[Genetics of Hirschsprung disease].Semantic proximity Read ↗

New roles of EDNRB and EDN3 in the pathogenesis of Hirschsprung disease.Semantic proximity Read ↗

[Genetics of Hirschsprung disease].Semantic proximity Read ↗

Targeting of endothelin receptor‐B to the neural crestSemantic proximity Read ↗

Mutations of the endothelin-B receptor and endothelin-3 genes in Hirschsprung's disease.Semantic proximity Read ↗

Spatiotemporal regulation of endothelin receptor-B by SOX10 in neural crest–derived enteric neuron precursorsSemantic proximity Read ↗

[Molecular genetics of Hirschsprung disease: a model of multigenic neurocristopathy].Semantic proximity Read ↗

Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system developmentSemantic proximity Read ↗

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