[Molecular basis of Hirschsprung disease].

Abstract excerpt

Hirschsprung disease (HSCR) is a congenital malformation caused by the absence of ganglion cells in the myenteric and submucosal plexuses of the gut. Recent studies have shown that mutations in the RET, glial-cell-derived neurotrophic factor (GDNF), endothelin-B receptor (EDNRB), endothelin-3 genes are responsible for the occurrence of aganglionosis. Those genes are involved in the development of neural crest...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Drosophila Proteins
• Share to RET gene
• Share to Mutation