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Article

Altered endothelin-3 and endothelin-B receptor mRNA expression in Hirschsprung's disease.

Journal of pediatric surgery - 1 Aug 1999

Oue T, Puri P

Abstract excerpt

BACKGROUND: Recently, the endothelin-3 (EDN3) and endothelin-B receptor (EDNRB) gene have been recognized as susceptibility genes for Hirschsprung's disease (HD). However, gene mutations have been observed only in limited cases, and the role of EDN3 in the pathogenesis and motility dysfunction in HD is not understood fully. To evaluate the possible implication of EDN3 and EDNRB for the development of HD, we...

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Source

Identifiers

PMID: 10466607
DOI: 10.1016/s0022-3468(99)90163-x

Genes

EDN3
EDNRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Altered endothelin-3 and endothelin-B receptor mRNA expression in Hirschsprung's disease.PMID 10466607Read ↗

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[Endothelin B receptor system and Hirschsprung disease].Semantic proximity Read ↗

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Novel mutations of the endothelin B receptor gene in patients with Hirschsprung's disease and their characterization.Semantic proximity Read ↗

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Endothelin-3 Gene Mutations in Isolated and Syndromic Hirschsprung DiseaseSemantic proximity Read ↗

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