Article
5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease.
Human molecular genetics - 1 Sept 1998
Holmes C, Arranz M J, Powell J F, Collier D A, Lovestone S
Abstract excerpt
The psychopathology of Alzheimer's disease (AD) is varied and includes both behavioural and psychological symptoms. Behavioural and psychological symptoms are common and contribute to the difficulties experienced by carers. However, the mechanism whereby these symptoms occur in some individuals with AD is not understood. We hypothesized that common genetic polymorphisms in neurotransmitter systems are risk...
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