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Association between 5-HT(2A) receptor polymorphism and psychotic symptoms in Alzheimer's disease.

Biological psychiatry - 15 Sept 2001

Nacmias B, Tedde A, Forleo P, Piacentini S, Guarnieri B M, Bartoli A, Ortenzi L, Petruzzi C, Serio A, Marcon G, Sorbi S

Abstract excerpt

BACKGROUND: The aim of this study is to analyze the segregation of the 102T/C polymorphism in the serotonin 2A receptor gene in patients affected by sporadic and familial Alzheimer's disease (FAD) with and without psychotic symptoms. METHODS: The polymorphism was analyzed in 275 subjects. A semistructured interview was used to obtain information about delusions, hallucinations, and other specific behavioral signs...

Topics

Aged
Alzheimer Disease
Apolipoproteins E
Female
Gene Amplification
Gene Expression
Gene Frequency
Genotype
Homozygote
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Point Mutation

Polymorphism, Genetic

Psychotic Disorders

Receptors, Serotonin

Source

Identifiers

PMID: 11566166
DOI: 10.1016/s0006-3223(01)01114-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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