Article
Association between 5-HT(2A) receptor polymorphism and psychotic symptoms in Alzheimer's disease.
Biological psychiatry - 15 Sept 2001
Nacmias B, Tedde A, Forleo P, Piacentini S, Guarnieri B M, Bartoli A, Ortenzi L, Petruzzi C, Serio A, Marcon G, Sorbi S
Abstract excerpt
BACKGROUND: The aim of this study is to analyze the segregation of the 102T/C polymorphism in the serotonin 2A receptor gene in patients affected by sporadic and familial Alzheimer's disease (FAD) with and without psychotic symptoms. METHODS: The polymorphism was analyzed in 275 subjects. A semistructured interview was used to obtain information about delusions, hallucinations, and other specific behavioral signs...
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