Article
No effect of the alpha1-antichymotrypsin A allele in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry - 1 Jul 1997
Didierjean O, Martinez M, Campion D, Hannequin D, Dubois B, Martin C, Puel M, Thomas Anterion C, Pasquier F, Moreau O, Babron M C, Penet C, Agid Y, Clerget-Darpoux F, Frebourg T, Brice A
Abstract excerpt
The apolipoprotein E (ApoE)-epsilon4 allele is associated in a dose dependent manner to an increased risk for Alzheimer's disease. However, the ApoE-epsilon4 allele effect does not account for all patients with Alzheimer's disease, and the existence of other genetic risk factors has been postulated. Kamboh et al reported an association between Alzheimer's disease and the A allele of alpha1-antichymotrypsin (Aact)...
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