Article
Identification of specific nucleotide sequences within the conserved 3'-SL in the dengue type 2 virus genome required for replication.
Journal of virology - 1 Sept 1998
Zeng L, Falgout B, Markoff L
Abstract excerpt
The flavivirus genome is a positive-stranded approximately 11-kb RNA including 5' and 3' noncoding regions (NCR) of approximately 100 and 400 to 600 nucleotides (nt), respectively. The 3' NCR contains adjacent, thermodynamically stable, conserved short and long stem-and-loop structures (the 3'-SL...
Topics
- Animals
- Base Sequence
- Cell Line
- Conserved Sequence
- Dengue Virus
- Electronic Data Processing
- Genome, Viral
- Kinetics
- Macaca mulatta
- Molecular Sequence Data
- Mutagenesis
- Nucleic Acid Conformation
- Phenotype
- RNA, Viral
- Structure-Activity Relationship
- Viral Plaque Assay
- Viral Proteins
- Virus Replication