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Article

A single genetic origin for the common prothrombotic G20210A polymorphism in the prothrombin gene.

Blood - 15 Aug 1998

Zivelin A, Rosenberg N, Faier S, Kornbrot N, Peretz H, Mannhalter C, Horellou M H, Seligsohn U

Abstract excerpt

The polymorphism G20210A in the 3' untranslated region of the prothrombin gene is associated with an increased level of factor II activity and confers a twofold to fivefold increase in the risk for venous thromboembolism. Among Caucasian populations, the prevalence of factor II G20210A heterozygotes is 1% to 6%, whereas in non-Caucasian populations it is very rare or absent. The aim of the present study was to...

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PMID: 9694698

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A single genetic origin for the common prothrombotic G20210A polymorphism in the prothrombin gene.PMID 9694698Read ↗

Prevalence of the G20210A polymorphism in the 3'-untranslated region of the prothrombin gene in different human populations.Semantic proximity Read ↗

Global prevalence of prothrombin gene mutation G20210A and implications in women's health: a systematic review.Semantic proximity Read ↗

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis.Semantic proximity Read ↗

The heterozygous 20210 G/A prothrombin genotype is associated with early venous thrombosis in inherited thrombophilias and is not increased in frequency in artery disease.Semantic proximity Read ↗

The 20210 A allele of the prothrombin gene is a common risk factor among Swedish outpatients with verified deep venous thrombosis.Semantic proximity Read ↗

The prothrombin 20210 G to A variation and thrombosis.Semantic proximity Read ↗

Prevalence of genetic prothrombotic risk factors: 1691G > A FV, 20210G > A PT and 677C > T MTHFR mutations in the Bosnian population.Semantic proximity Read ↗

The prothrombin 20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population.Semantic proximity Read ↗

The prothrombin nt20210 A allele as a risk factor for venous thromboembolism: detection of heterozygous and homozygous carriers by alternative methods.Semantic proximity Read ↗

Activated protein C resistance caused by a common factor V mutation has a single origin.Semantic proximity Read ↗

Prevalence of 20210 A allele of the prothrombin gene in venous thromboembolism patients.Semantic proximity Read ↗

The prothrombin gene G20210A variant: prevalence in a U.K. anticoagulant clinic populationSemantic proximity Read ↗

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