Article
Unraveling the molecular landscape of kAE1: a narrative review.
Canadian journal of physiology and pharmacology - 1 Jul 2024
Mungara Priyanka, Waiss Moubarak, Hartwig Sunny, Burger Dylan, Cordat Emmanuelle
Abstract excerpt
Kidney anion exchanger 1 (kAE1) is an isoform of the AE1 protein encoded by the SLC4A1 gene. It is a basolateral membrane protein expressed by α-intercalated cells in the connecting tubules and collecting duct of the kidney. Its main function is to exchange bicarbonate and chloride ions between the blood and urine to maintain blood pH at physiological threshold. The kAE1 protein undergoes multiple...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
