Article
Angiotensin-converting enzyme gene polymorphism and reversibility of uremic left ventricular hypertrophy following long-term antihypertensive therapy.
Kidney international - 1 Aug 1998
Cannella G, Paoletti E, Barocci S, Massarino F, Delfino R, Ravera G, Di Maio G, Nocera A, Patrone P, Rolla D
Abstract excerpt
BACKGROUND: Prolonged antihypertensive therapy might be less effective in reversing the left ventricular hypertrophy (LVH) in uremics bearing the deleted (DD) allele of the angiotensin converting enzyme (ACE) gene than in patients with the inserted (II) allele or in those heterozygous (ID) for the gene. METHODS: Thirteen DD and 17 II + ID hemodialyzed uremics were followed-up with yearly echocardiography and...
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