Article
[Congenital multiple anterior pituitary hormone deficiencies. An approach of pituitary ontogenesis].
Annales d'endocrinologie - 1 Jan 1997
Brue T, Vallette S, Pellegrini-Bouiller I, Enjalbert A
Abstract excerpt
A number of transcription factors evidenced in the pituitary may play a part in the development of this gland, namely Pit-1, Prop-1, P-Lim, Ptx1, Rpx, Dax-1, SF-1. Several of these factors are involved in animal models of hypopituitarism, while up to now only Pit-1 gene alterations have been shown to be responsible for hypopituitarism in man. These factors are briefly presented, and current data on genetically...
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