Article
[Congenital multiple anterior pituitary hormone deficiencies. An approach of pituitary ontogenesis].
Annales d'endocrinologie - 1 Jan 1997
Brue T, Vallette S, Pellegrini-Bouiller I, Enjalbert A
Abstract excerpt
A number of transcription factors evidenced in the pituitary may play a part in the development of this gland, namely Pit-1, Prop-1, P-Lim, Ptx1, Rpx, Dax-1, SF-1. Several of these factors are involved in animal models of hypopituitarism, while up to now only Pit-1 gene alterations have been show...
Topics
- Animals
- DNA-Binding Proteins
- Disease Models, Animal
- Gene Expression Regulation, Developmental
- Homeodomain Proteins
- Hypopituitarism
- Mice
- Phenotype
- Pituitary Gland, Anterior
- Pituitary Hormones, Anterior
- Transcription Factor Pit-1
- Transcription Factors