Article
Pituitary Hypoplasia.
Endocrinology and metabolism clinics of North America - 1 Jun 2017
Gangat Mariam, Radovick Sally
Abstract excerpt
This article summarizes pituitary development and function as well as specific mutations of genes encoding the following transcription factors: HESX1, LHX3, LHX4, POU1F1, PROP1, and OTX2. Although several additional genetic defects related to hypopituitarism have been identified, this article focuses on these selected factors, as they have been well described in the literature in terms of clinical...
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