Article
Linkage and association of HLA class II genes with vitiligo in a Dutch population.
The British journal of dermatology - 1 Jul 2001
Zamani M, Spaepen M, Sghar S S, Huang C, Westerhof W, Nieuweboer-Krobotova L, Cassiman J J
Abstract excerpt
BACKGROUND: Serological typing of HLA has shown discrepancies in HLA associations with vitiligo in different ethnic populations. OBJECTIVES: To perform genotyping of HLA class II genes on a Dutch vitiligo population in order clearly to identify susceptible and protective HLA alleles in vitiligo. METHODS: HLA typing was carried out by amplifying genomic DNA by polymerase chain reaction (PCR) followed by dot-blot...
Topics
- Adolescent
- Adult
- Alleles
- Case-Control Studies
- Child
- Child, Preschool
- Female
- Genes, MHC Class II
- Genetic Linkage
- Genetic Predisposition to Disease
- Haplotypes
- Histocompatibility Testing
- Humans
- Male
- Middle Aged
- Netherlands
- Vitiligo
