Article
Production of soluble single-chain T-cell receptor fragments in Escherichia coli trxB mutants.
Molecular immunology - 1 Feb 1998
Molloy P E, Harris W J, Strachan G, Watts C, Cunningham C
Abstract excerpt
Antibodies and T cell receptors (TCR) both belong to the immunoglobulin superfamily whose members are characterised by the possession of one or more immunoglobulin domains. The production of soluble single chain antibody fragments in Escherichia coli has, in recent years, become a routine laborat...
Topics
- Amino Acid Sequence
- Animals
- Blotting, Western
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Humans
- Mice
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Receptors, Antigen, T-Cell, alpha-beta
- Thioredoxin-Disulfide Reductase
