Article
Protection of chickens against experimental fowl typhoid using a nuoG mutant of Salmonella serotype Gallinarum.
Vaccine - 1 Jan 2000
Zhang-Barber L, Turner A K, Dougan G, Barrow P A
Abstract excerpt
A nuoG mutation in NADH dehydrogenase I was introduced into a virulent strain of Salmonella serotype Gallinarum, the causative agent of fowl typhoid, using gene replacement with a nuoG open reading frame inactivated by insertion of DNA encoding a kanamycin resistance determinant. The S. Gallinaru...
Topics
- Animals
- Bacterial Vaccines
- Base Sequence
- Chickens
- DNA Primers
- Electron Transport Complex I
- Genes, Bacterial
- Mononuclear Phagocyte System
- Mutagenesis, Insertional
- Mutation
- NADH, NADPH Oxidoreductases
- Polymerase Chain Reaction
- Poultry Diseases
- Salmonella
- Salmonella Infections, Animal
- Serotyping
- Vaccines, Attenuated
- Virulence