Article
Cis-acting elements required for strong stop acceptor template selection during Moloney murine leukemia virus reverse transcription.
Journal of molecular biology - 7 Aug 1998
Topping R, Demoitie M A, Shin N H, Telesnitsky A
Abstract excerpt
Template switching is required during normal retroviral DNA synthesis and is involved in retroviral genetic recombination. The first strong stop template switch during Moloney murine leukemia virus reverse transcription was studied to examine how template switch acceptor templates are selected. Retroviral vectors with specific alterations in their template switch acceptor regions were constructed, and DNA...
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