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Article

Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by <i>Streptomyces antibioticus</i>

1 Jun 1998

Abstract excerpt

A 5.2 kb region from the oleandomycin gene cluster in Streptomyces antibioticus located between the oleandomycin polyketide synthase gene and sugar biosynthetic genes was cloned. Sequence analysis revealed the presence of three open reading frames (designated oleI, oleN2 and oleR). The oleI gene product resembled glycosyltransferases involved in macrolide inactivation including the oleD product, a previously...

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PMID: 9680207
DOI: 10.1046/j.1365-2958.1998.00880.x

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Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by <i>Streptomyces antibioticus</i>PMID 9680207Read ↗

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