Article
Induction of S100b in myocardium: an intrinsic inhibitor of cardiac hypertrophy.
Canadian journal of applied physiology = Revue canadienne de physiologie appliquee - 1 Aug 1998
Parker T G, Marks A, Tsoporis J N
Abstract excerpt
Cardiac hypertrophy induced by pressure overload and following myocardial infarction entails regulation of myocardial gene expression, recapitulating an embryonic phenotype, including activation of fetal beta-myosin heavy chain and skeletal alpha-actin. Progressive hypertrophy and alterations in...
Topics
- Actins
- Animals
- Cardiac Output, Low
- Cardiomegaly
- Cell Division
- Cells, Cultured
- Disease Models, Animal
- Feedback
- Gene Expression Regulation
- Humans
- Mice
- Mice, Transgenic
- Myocardial Infarction
- Myocardium
- Myosin Heavy Chains
- Nonmuscle Myosin Type IIB
- Phenotype
- Protein Kinase C
