Article
Induction of S100b in myocardium: an intrinsic inhibitor of cardiac hypertrophy.
Canadian journal of applied physiology = Revue canadienne de physiologie appliquee - 1 Aug 1998
Parker T G, Marks A, Tsoporis J N
Abstract excerpt
Cardiac hypertrophy induced by pressure overload and following myocardial infarction entails regulation of myocardial gene expression, recapitulating an embryonic phenotype, including activation of fetal beta-myosin heavy chain and skeletal alpha-actin. Progressive hypertrophy and alterations in gene expression may contribute to myocardial failure. Although signaling pathways that contribute to hypertrophy...
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