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Article

S100beta inhibits alpha1-adrenergic induction of the hypertrophic phenotype in cardiac myocytes.

The Journal of biological chemistry - 12 Dec 1997

Tsoporis J N, Marks A, Kahn H J, Butany J W, Liu P P, O'Hanlon D, Parker T G

Abstract excerpt

In an experimental rat model of myocardial infarction, surviving cardiac myocytes undergo hypertrophy in response to trophic effectors. This response involves gene reprogramming manifested by the re-expression of fetal genes, such as the previously reported isoform switch from adult alpha- to embryonic beta-myosin heavy chain. We now report the transient re-expression of a second fetal gene, skeletal alpha-actin...

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Identifiers

PMID: 9395540
DOI: 10.1074/jbc.272.50.31915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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