Article
Structure/function relationship studies on the T/S residues 173-177 of rat ODC.
Biochimica et biophysica acta - 28 Jul 1998
Matés J M, del Valle A E, Urdiales J L, Coleman C S, Feith D, Olmo M T, Pegg A E, Sánchez-Jiménez F
Abstract excerpt
A well-conserved T/S cluster was detected among vertebrate ornithine decarboxylase by computer analysis (E. Viguera, O. Trelles, J.L. Urdiales, J.M. Matés, F. Sánchez-Jiménez, Trends Biochem. Sci. 19 (1994) 318-319). In the present report we studied the role of these residues (173, 176 and 177 in...
Topics
- Amino Acid Sequence
- Animals
- Conserved Sequence
- DNA Mutational Analysis
- Enzyme Stability
- Eukaryotic Cells
- Mammals
- Mutation
- Ornithine Decarboxylase
- Peptide Fragments
- Rats
- Recombinant Proteins
- Serine
- Structure-Activity Relationship
- Threonine
- Trypanosoma brucei brucei