Article
Critical factors determining dimerization of human antizyme inhibitor.
The Journal of biological chemistry - 25 Sept 2009
Su Kuo-Liang, Liao Ya-Fan, Hung Hui-Chih, Liu Guang-Yaw
Abstract excerpt
Ornithine decarboxylase (ODC) is the first enzyme involved in polyamine biosynthesis, and it catalyzes the decarboxylation of ornithine to putrescine. ODC is a dimeric enzyme, whereas antizyme inhibitor (AZI), a positive regulator of ODC that is homologous to ODC, exists predominantly as a monome...
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