Article
Bacterial expression and characterization of human recombinant apolipoprotein(a) kringle IV type 9.
Protein expression and purification - 1 Jul 1998
Chung F Z, Wu L H, Lee H T, Mueller W T, Spahr M A, Eaton S R, Tian Y, Settimi P D, Oxender D L, Ramharack R
Abstract excerpt
Elevated plasma lipoprotein(a) [Lp(a)] is an independent risk factor for several vascular diseases. Lp(a) particles are generated through the formation of a disulfide bond between Cys4057 of kringle IV type 9, (KIVt9), of the multikringle apolipoprotein(a) [apo(a)] and a cysteine in apoB-100 low-...
Topics
- Apolipoprotein B-100
- Apolipoproteins B
- Cysteine
- Disulfides
- Escherichia coli
- Humans
- Kringles
- Lipoprotein(a)
- Models, Molecular
- Mutation
- Peptide Fragments
- Peptides