Article
Optimized bacterial expression of human apolipoprotein A-I.
Protein expression and purification - 1 Jan 2003
Ryan Robert O, Forte Trudy M, Oda Michael N
Abstract excerpt
Apolipoprotein A-I (apoA-I) serves critical functions in plasma lipoprotein metabolism as a structural component of high density lipoprotein, activator of lecithin:cholesterol acyltransferase, and acceptor of cellular cholesterol as part of the reverse cholesterol transport pathway. In an effort to facilitate structure:function studies of human apoA-I, we have optimized a plasmid vector for production of...
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