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Cell Arrest and Cell Death in Mammalian Preimplantation Development: Lessons from the Bovine Model

21 Jul 2011

Abstract excerpt

BACKGROUND: The causes, modes, biological role and prospective significance of cell death in preimplantation development in humans and other mammals are still poorly understood. Early bovine embryos represent a very attractive experimental model for the investigation of this fundamental and important issue. METHODS AND FINDINGS: To obtain reference data on the temporal and spatial occurrence of cell death in...

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PMID: 21811561
DOI: 10.1371/journal.pone.0022121

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