Article
Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism.
Archives of general psychiatry - 1 Jul 1991
Noble E P, Blum K, Ritchie T, Montgomery A, Sheridan P J
Abstract excerpt
The allelic association of the human D2 dopamine receptor gene with the binding characteristics of the D2 dopamine receptor was determined in 66 brains of alcoholic and non-alcoholic subjects. In a blinded experiment, DNA from the cerebral cortex was treated with the restriction endonuclease Taql and probed with a 1.5-kilobase (kb) digest of a clone (lambda hD2G1) of the human D2 dopamine receptor gene. The...
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