Article
Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism.
Archives of general psychiatry - 1 Jul 1991
Noble E P, Blum K, Ritchie T, Montgomery A, Sheridan P J
Abstract excerpt
The allelic association of the human D2 dopamine receptor gene with the binding characteristics of the D2 dopamine receptor was determined in 66 brains of alcoholic and non-alcoholic subjects. In a blinded experiment, DNA from the cerebral cortex was treated with the restriction endonuclease Taql...
Topics
- Alcoholism
- Alleles
- Caudate Nucleus
- DNA Probes
- Female
- Humans
- Male
- Middle Aged
- Protein Binding
- Receptors, Dopamine
- Spiperone
- Tritium
