Article
Identification of amino acids involved in a serotype and neutralization specific epitope within the s1 subunit of avian infectious bronchitis virus.
Archives of virology - 1 Jan 1997
Moore K M, Jackwood M W, Hilt D A
Abstract excerpt
Localization of neutralizing, serotype specific epitopes of infectious bronchitis virus has been difficult because these epitopes are conformationally dependent. We identified amino acids involved in a serotype specific, conformationally dependent epitope by analysis of the S1 gene of 13 monoclon...
Topics
- Amino Acids
- Animals
- Antibodies, Monoclonal
- Antibodies, Viral
- Antigens, Viral
- Chick Embryo
- Epitope Mapping
- Epitopes, B-Lymphocyte
- Glycosylation
- Infectious bronchitis virus
- Membrane Glycoproteins
- Mutation
- Neutralization Tests
- Protein Structure, Secondary
- Sequence Analysis, DNA
- Serotyping
- Spike Glycoprotein, Coronavirus
- Viral Envelope Proteins