Article
Efficacy of interferon dose and prediction of response in chronic hepatitis C: Benelux study in 336 patients.
Journal of hepatology - 1 Jun 1998
Brouwer J T, Nevens F, Kleter B, Elewaut A, Adler M, Brenard R, Chamuleau R A, Michielsen P P, Pirotte J, Hautekeete M L, Weber J, Bourgeois N, Hansen B E, Bronkhorst C M, ten Kate F J, Heijtink R A, Fevery J, Schalm S W
Abstract excerpt
BACKGROUND/AIMS: In an attempt to improve the limited efficacy of treatment of chronic hepatitis C with interferon-alpha 3 MU tiw, we studied the effects of double-dose therapy followed by downward titration, and analyzed the pre- and pertreatment factors associated with response or non-response....
Topics
- Adult
- Aged
- Alanine Transaminase
- Antiviral Agents
- Aspartate Aminotransferases
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Female
- Follow-Up Studies
- Genotype
- Hepacivirus