Article
DNA binding by the KP repressor protein inhibits P-element transposase activity in vitro.
The EMBO journal - 15 Jul 1998
Lee C C, Beall E L, Rio D C
Abstract excerpt
P elements are a family of mobile DNA elements found in Drosophila. P-element transposition is tightly regulated, and P-element-encoded repressor proteins are responsible for inhibiting transposition in vivo. To investigate the molecular mechanisms by which one of these repressors, the KP protein, inhibits transposition, a variety of mutant KP proteins were prepared and tested for their biochemical activities....
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