Boundary formation in Drosophila wing: Notch activity attenuated by the POU protein Nubbin.

doi:10.1126/science.281.5375.409

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Article

Boundary formation in Drosophila wing: Notch activity attenuated by the POU protein Nubbin.

Science (New York, N.Y.) - 17 Jul 1998

Neumann C J, Cohen S M

Abstract excerpt

Cell interactions mediated by Notch-family receptors have been implicated in the specification of tissue boundaries in vertebrate and insect development. Although Notch ligands are often widely expressed, tightly localized activation of Notch is critical for the formation of sharp boundaries. Evi...

Topics

Animals
Calcium-Binding Proteins
Drosophila
Drosophila Proteins
Enhancer Elements, Genetic
Gene Expression Regulation
Genes, Insect
Homeodomain Proteins
Insect Proteins
Intercellular Signaling Peptides and Proteins
Intracellular Signaling Peptides and Proteins
Jagged-1 Protein
Ligands
Membrane Proteins
Mutation
N-Acetylglucosaminyltransferases
Nuclear Proteins
POU Domain Factors

Source

Open in PubMed

Identifiers

PMID: 9665883
DOI: 10.1126/science.281.5375.409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9665883-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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