Article
fringe, a Boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development.
Cell - 18 Nov 1994
Irvine K D, Wieschaus E
Abstract excerpt
Wing formation in Drosophila requires interactions between dorsal and ventral cells. We describe a new gene, fringe, which is expressed in dorsal cells and encodes for a novel protein that is predicted to be secreted. Wing margin formation and distal wing outgrowth can be induced by the juxtaposi...
Topics
- Amino Acid Sequence
- Animals
- Cloning, Molecular
- Crosses, Genetic
- Drosophila
- Drosophila Proteins
- Female
- Gene Expression
- Larva
- Male
- Molecular Sequence Data
- Mutagenesis
- N-Acetylglucosaminyltransferases
- Open Reading Frames
- Phenotype
- Protein Biosynthesis
- Proteins
- Signal Transduction