Article
Constitutive expression of HGF modulates renal epithelial cell phenotype and induces c-met and fibronectin expression.
Experimental cell research - 10 Jul 1998
Liu Y, Centracchio J N, Lin L, Sun A M, Dworkin L D
Abstract excerpt
Hepatocyte growth factor (HGF) is a potent renotropic factor that has been shown to play important roles in kidney development and recovery from acute renal injury. To examine the effects of HGF on renal tubular epithelium, we generated HGF-producing renal epithelial cells by stably transfecting mIMCD-3 and OK cells with an expression plasmid containing human HGF cDNA. Expression of HGF in the transfected cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
