Article
Molecular characterization and liposomal transfection of a p53-mutated cell line established from a poorly differentiated leiomyosarcoma.
International journal of oncology - 1 Aug 1998
Meye A, Bache M, Hinze R, Schmidt H, Würl P, Holzhausen H J, Rath F W, Taubert H
Abstract excerpt
A human cell line LMS6-93 has been established from a leiomyosarcoma (LMS). Characteristics for ultrastructure, growth characteristics, cell cycle distribution, karyotype, protein expression detected by immunohistochemistry (IHC), p53 mutational status and liposomal transfection behaviour were st...
Topics
- Blotting, Western
- Cell Differentiation
- Cell Division
- Cyclin-Dependent Kinase Inhibitor p16
- DNA Mutational Analysis
- DNA, Neoplasm
- Genes, p16
- Genes, p53
- Genes, ras
- Humans
- Immunohistochemistry
- Karyotyping
- Leiomyosarcoma
- Liposomes
- Lung Neoplasms
- Male
- Middle Aged
- Mutation