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Article

Three births after preimplantation genetic diagnosis for cystic fibrosis with sequential first and second polar body analysis.

American journal of obstetrics and gynecology - 1 Jun 1998

Strom C M, Ginsberg N, Rechitsky S, Cieslak J, Ivakhenko V, Wolf G, Lifchez A, Moise J, Valle J, Kaplan B, White M, Barton J, Kuliev A, Verlinsky Y

Abstract excerpt

OBJECTIVE: The purpose of this study was to determine the accuracy and feasibility of sequential polar body removal and analysis for preimplantation genetic diagnosis of mendelian disorders. STUDY DESIGN: Three couples with risk factors for cystic fibrosis had preimplantation genetic diagnosis with the use of sequential polar body analysis. After stimulation, oocytes were harvested and the first polar bodies were...

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Identifiers

PMID: 9662315
DOI: 10.1016/s0002-9378(98)70336-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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