Article
Fibroblast heterogeneity of signal transduction mechanisms to complement-C1q. Analyses of calcium mobilization, inositol phosphate accumulation, and protein kinases-C redistribution.
Journal of periodontology - 1 Jun 1998
Bordin S, Costa L G, Tan X
Abstract excerpt
Fibroblasts of healthy and granulation gingiva are phenotypically heterogeneous with regard to binding C1q collagen-like (cC1qR) or C1q globular-heads (gC1qR) regions, respectively. Here, isolated fibroblast subsets, expressing either the cC1qR or the gC1qR phenotype, were stimulated with C1q, an...
Topics
- Analysis of Variance
- Antibodies
- Blotting, Western
- Calcium
- Cell Line
- Cell Membrane
- Collagen
- Complement C1q
- Complement System Proteins
- Cytosol
- Fibroblasts
- Flow Cytometry
- Fluorescent Dyes
- Gene Expression
- Gingiva
- Granulation Tissue
- Humans
- Indoles