Article
Phenotypic characteristics of dengue 2 virus persistently infected in a C6/36 clone of Aedes albopictus cells.
Intervirology - 1 Jan 1994
Chen W J, Chen S L, Fang A H
Abstract excerpt
A C6/36 cell culture persistently infected by dengue 2 virus was established and retained for over 20 weeks. No CPE was observed at any stage of infection. However, some giant cells up to 2- or 3-fold the diameter of normal cells appeared in the established culture. Extracellular virus titers fluctuated with a periodic tendency while the antigen level remained constant, suggesting some viral particles evolved...
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