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Article

Isolation, characterization and disruption of the casein kinase II alpha subunit gene of Leishmania chagasi.

Molecular and biochemical parasitology - 1 May 1998

Bhatia A, Sanyal R, Paramchuk W, Gedamu L

Abstract excerpt

To elucidate the role played by casein kinase II in Leishmania survival, we have isolated and characterized the Leishmania chagasi casein kinase II alpha subunit cDNA, (L.c CKIIalpha). The 1083 bp coding region is flanked by 148 bp of 5' UTR and 1155 bp of 3' UTR. L.c CKIIalpha shows a remarkable degree of similarity with other isolated casein kinase II alpha subunit sequences. L.c CKIIalpha protein is encoded by...

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PMID: 9657325
DOI: 10.1016/s0166-6851(98)00002-4

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