Article
Isolation, characterization and disruption of the casein kinase II alpha subunit gene of Leishmania chagasi.
Molecular and biochemical parasitology - 1 May 1998
Bhatia A, Sanyal R, Paramchuk W, Gedamu L
Abstract excerpt
To elucidate the role played by casein kinase II in Leishmania survival, we have isolated and characterized the Leishmania chagasi casein kinase II alpha subunit cDNA, (L.c CKIIalpha). The 1083 bp coding region is flanked by 148 bp of 5' UTR and 1155 bp of 3' UTR. L.c CKIIalpha shows a remarkable...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Anti-Bacterial Agents
- Blotting, Northern
- Blotting, Southern
- Casein Kinase II
- Cinnamates
- DNA, Complementary
- Enzyme Activation
- Gene Expression Regulation
- Hygromycin B
- In Vitro Techniques
- Leishmania
- Molecular Sequence Data
- Mutagenesis
- Polymerase Chain Reaction
- Protein Serine-Threonine Kinases