Characterisation of Casein Kinase 1.1 inLeishmania donovaniUsing the CRISPR Cas9 Toolkit

Abstract excerpt

The recent adaptation of CRISPR Cas9 genome editing toLeishmaniaspp. has opened a new era in decipheringLeishmaniabiology. The method was recently improved using a PCR-based CRISPR Cas9 approach, which eliminated the need for cloning. This new approach, which allows high-throughput gene deletion, was successfully validated inL. mexicanaandL. major. In this study, we validated the toolkit inLeishmania...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CRISPR and Genetic Engineering
• Share to Research on Leishmaniasis Studies
• Share to Trypanosoma species research and implications