Article
Localization of signal recognition particle RNA in the nucleolus of mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America - 7 Jul 1998
Jacobson M R, Pederson T
Abstract excerpt
The signal recognition particle (SRP) of eukaryotic cells is a cytoplasmic ribonucleoprotein machine that arrests the translational elongation of nascent secretory and membrane proteins and facilitates their transport into the endoplasmic reticulum. The spatial pathway of SRP RNA processing and ribonucleoprotein assembly in the cell is not known. In the present investigation, microinjection of fluorescently...
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