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Article

Cell Cycle Dependent Nucleolar Localization of the Coronavirus Nucleocapsid Protein

1 Apr 2007

Abstract excerpt

The nucleolus is a dynamic sub-nuclear structure which is involved in ribosome subunit biogenesis, modulation of cell growth and response to cell stress. The nucleolar proteome varies particularly with regard to the cell cycle. Viral proteins can localise to the nucleolus and using the coronavirus nucleocapsid (N) protein as a model, the cell cycle dependent trafficking of viral proteins to the nucleolus was...

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PMID: 17426449
DOI: 10.4161/cc.6.7.4032

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