Article
Analysis of mechanisms of epidermal proliferation induced by intracutaneous injection of cholera toxin by the use of site-specifically mutated cholera toxins.
Journal of dermatological science - 1 Mar 1998
Yamaoka J, Imamura S
Abstract excerpt
Intracutaneous injection of cholera toxin (CT) into rabbits increases vascular permeability and induces epidermal proliferation. To understand the mechanisms of these effects on the skin, we evaluated the involvement of the ADP-ribosyltransferase activity of the A subunit of CT and receptor-bindi...
Topics
- Animals
- CHO Cells
- Capillary Permeability
- Cell Division
- Chemical Phenomena
- Chemistry, Physical
- Cholera Toxin
- Cricetinae
- Epidermal Cells
- Epidermis
- Injections, Intradermal
- Mutagenesis, Site-Directed
- Mutation
- Rabbits
- Recombinant Proteins
