Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tyrphostin A9 and wortmannin perturb the Golgi complex and block proliferation of vascular smooth muscle cells.

European journal of cell biology - 1 May 1998

Thyberg J

Abstract excerpt

To proliferate, vascular smooth muscle cells first convert from a contractile to a synthetic phenotype. Earlier studies indicate that this process is supported by fibronectin and accelerated by platelet-derived growth factor (PDGF). Here, the mechanisms in this transition were further explored. Isolated rat aortic smooth muscle cells were treated with tyrphostin A9, a PDGF receptor tyrosine kinase inhibitor, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Cells, Cultured
Share to Enzyme Inhibitors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Golgi Apparatus

Share to Phenotype

Share to Rats, Sprague-Dawley

Share to Receptor Protein-Tyrosine Kinases

Source

Identifiers

PMID: 9650781
DOI: 10.1016/S0171-9335(98)80015-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Tyrphostin A9 and wortmannin perturb the Golgi complex and block proliferation of vascular smooth muscle cells.PMID 9650781Read ↗

Phenotypic conversion leads to structural and functional changes of smooth muscle sarcolemma.Semantic proximity Read ↗

Caveolae and cholesterol distribution in vascular smooth muscle cells of different phenotypes.Semantic proximity Read ↗

Dystrophin does not influence regular cytoskeletal architecture but is required for contractile performance in smooth muscle aortic cells.Semantic proximity Read ↗

Phenotype modulation in primary cultures of aortic smooth muscle cells from streptozotocin-diabetic rats.Semantic proximity Read ↗

Caldesmon regulates the motility of vascular smooth muscle cells by modulating the actin cytoskeleton stability.Semantic proximity Read ↗

Differential processing of osteopontin characterizes the proliferative vascular smooth muscle cell phenotype induced by allylamine.Semantic proximity Read ↗

Expression of caveolae on the surface of rat arterial smooth muscle cells is dependent on the phenotypic state of the cells.Semantic proximity Read ↗

Phenotypic modulation by fibronectin enhances the angiotensin II-generating system in cultured vascular smooth muscle cells.Semantic proximity Read ↗

Stretch of the vascular wall induces smooth muscle differentiation by promoting actin polymerization.Semantic proximity Read ↗

Modulation of smooth muscle cell function: morphological evidence for a contractile to synthetic transition in the rat ventral prostate after castration.Semantic proximity Read ↗

Inhibitors of ADP-ribosylation suppress phenotypic modulation and proliferation of smooth muscle cells cultured from rat aorta.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.