Article
Caveolae and cholesterol distribution in vascular smooth muscle cells of different phenotypes.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Feb 2002
Thyberg Johan
Abstract excerpt
Vascular smooth muscle cells (SMCs) grown in primary culture are converted from a contractile to a synthetic phenotype. This includes a marked morphological reorganization, with loss of myofilaments and formation of a large ER-Golgi complex. In addition, the number of cell surface caveolae is distinctly reduced and the handling of lipoprotein-derived cholesterol changed. Here we used filipin as a marker to study...
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