Article
Dystrophin does not influence regular cytoskeletal architecture but is required for contractile performance in smooth muscle aortic cells.
Cell biology international - 1 Oct 1994
Harricane M C, Fabbrizio E, Lees D, Prades C, Travo P, Mornet D
Abstract excerpt
Cultured vascular smooth muscle cells express distinct histological phenotypes due to a contractile to synthetic stage transition. In this study, we compared the behaviour of cultured aortic smooth muscle cells from young normal and mdx mice. Morphological, immunobiochemical, immunocytochemical analyses and contraction studies of these cells demonstrated that (i) the cell cytoskeleton in mdx mice is not affected...
Topics
- Animals
- Cells, Cultured
- Cytoskeletal Proteins
- Cytoskeleton
- Dystrophin
- Fluorescent Antibody Technique
- Membrane Proteins
- Mice
- Mice, Inbred C57BL
- Mice, Inbred mdx
- Muscle Contraction